The conformation of the nSrc specificity-determining loops in the Src and Abl SH3 domains are modulated by a WX conserved sequence motif
Frederick Longshore‐Neate, Caroline Ceravolo, Cole D. Masuga, Elise F. Tahti, Jadon M. Blount, Sarah N. Smith, Jeanine F. Amacher
This study investigates how the WX conserved sequence motif modulates the conformation of the nSrc loop in SH3 domains, affecting ligand specificity.
Frontiers in Molecular Biosciences · Dec 3, 2024Peer-reviewedBiochemistry