Cyclin-dependent kinase 2 (Cdk2) controls phosphatase-regulated signaling and function in platelets
Paul R. Woods, Brian L. Hood, Sruti Shiva, Thomas P. Conrads, Sarah Suchko, Richard A. Steinman
This study shows that Cdk2 is required for platelet activation by inhibiting PP1 phosphatase activity and promoting Erk activation through phosphorylation of PPP1R12a.
bioRxiv · May 31, 2020 · PreprintMolecular Biology