Tamoxifen transiently disrupts estrous cyclicity without altering long-term ovarian aging trajectories
Sarai Badillo, Ewa Poljanska, Sarah Ray, Hana H. Kilani, Jillian E. J. Cox, Sung-Hwan Ko, Subhasri Biswas, Doris M. Benbrook, Michael B. Stout, Sarah R. Ocañas
This study shows that tamoxifen temporarily disrupts estrous cycles but does not alter long-term ovarian aging patterns or transcriptional outcomes.
bioRxiv · Sep 8, 2026 · PreprintPhysiology