Jillian E. J. Cox

The paper identifies conserved sex-biased microglial responses to aging and amyloid pathology in mice and humans using single-cell transcriptomics and proteomics.

This study shows that tamoxifen temporarily disrupts estrous cycles but does not alter long-term ovarian aging patterns or transcriptional outcomes.

The paper compares tamoxifen-mediated cre induction efficiency and specificity in young and old mice, finding no significant difference in microglial labeling or translatomic changes.

The paper identifies sex differences in microglial transcriptomic and translatomic profiles in aging mouse hippocampus, highlighting female-biased senescence and disease-associated signatures linked to Alzheimer's disease.