Natural variants in C. elegans atg-5 3’UTR uncover divergent effects of autophagy on polyglutamine aggregation in different tissues
Jasmine Alexander-Floyd, Saroona Haroon, Ying Ma, Ariana A. Entezari, C Jaeger, Marc Vermulst, Tali Gidalevitz
The paper identifies a genetic variant in C. elegans atg-5 that alters autophagy's effect on polyglutamine aggregation, showing tissue-dependent outcomes.
bioRxiv · Jun 13, 2019 · PreprintGenetics