Structure of the human mitochondrial RNA degradosomereveals a distinct mode of helicase-nuclease coupling
Paula Favoretti Vital do Prado, Saruby Sharma, Arjun Bhatta, Ana N. Vučković, Maral Parvizian Marani, Andrei Philipp Llarena David, Bernhard Kuhle, Hauke S. Hillen
The paper determines the cryo-EM structure of the human mitochondrial RNA degradosome, revealing a unique helicase-nuclease coupling mechanism.
bioRxiv · Sep 10, 2026 · PreprintBiochemistry