Bernhard Kuhle

The paper determines the cryo-EM structure of the human mitochondrial RNA degradosome, revealing a unique helicase-nuclease coupling mechanism.

This study elucidates the mechanism of human tRNA 3'CCA maturation by determining TRNT1 structures and showing a continuous polymerization and translocation mechanism.

This study investigates the molecular interactions of eIF2β with eIF5, eIF2B, and 5MP1 using crystallography and NMR, revealing binding sites and regulatory roles of CK2 phosphorylation.

The paper identifies the molecular mechanisms by which ELAC2 processes nuclear and mitochondrial tRNAs, revealing distinct roles for TRMT10C and SDR5C1 in mitochondrial tRNA maturation.