Cancer BiologybioRxiv
Timp2 loss-of-function mutation and TIMP2 treatment in murine model of NSCLC: modulation of immunosuppression and oncogenic signaling
David Peeney, Sarvesh Kumar, Tej Pratap Singh…·William G. Stetler-Stevenson
TIMP2 treatment compensates for TIMP2 mutation to reveal immunomodulatory and oncogene regulation that inhibits tumor growth and metastatic niche formation.
DOI 10.1016/j.tranon.2025.102309