Constrained Transcriptional Polarity In The Organization Of Mammalian Hox Gene Clusters
Fabrice Darbellay, Célia Bochaton, Lucille Lopez‐Delisle, Bénédicte Mascrez, Patrick Tschopp, Saskia Delpretti, József Zákány, Denis Duboule
The paper investigates the role of uniform transcriptional orientation in mammalian Hox gene clusters by engineering inversions and observing their impact on gene regulation.
bioRxiv · Mar 11, 2019 · PreprintDevelopmental Biology