CMV-specific clonal expansion of Th1, GZMK⁺ CD8⁺, and TEMRA T cells revealed by human PBMC single cell profiling
Titas Grabauskas, Luke Trinity, Chris P. Verschoor, Djamel Nehar-Belaid, Radu Marcheş, Giray Naim Eryilmaz, Avinash S. Mahajan, Sathya Baarathi, Asa Thibodeau, Emilie Picard, Chia‐Ling Kuo, Kenneth E. Schmader, Cathleen S Colon-Emeric, Heather Elizabeth Whitson, Silke Paust, , Duygu Ucar
The paper uses single-cell profiling to show CMV drives clonal expansion of GZMK CD8 and Th1 cells in humans.
bioRxiv · Jun 24, 2025 · PreprintImmunology