Clonal Hematopoiesis Accelerates Frailty and Functional Decline
Kun Zhao, Candice Quin, Yash Pershad…·Alexander G. Bick
This study links clonal hematopoiesis to accelerated frailty and functional decline across multiple organ systems in humans.
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Health Sciences NorthORCID 0000-0001-6190-2655Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Kun Zhao, Candice Quin, Yash Pershad…·Alexander G. Bick
This study links clonal hematopoiesis to accelerated frailty and functional decline across multiple organ systems in humans.
Shreya Joshi, Aisha Nazli, Chris P. Verschoor, Charu Kaushic
The paper identifies hormone-specific microRNA signatures in vaginal epithelial cells and their effects on mRNA targets related to cell adhesion, immune response, and pathogen susceptibility.
Djamel Nehar-Belaid, Asa Thibodeau, Alper Eroğlu…·Duygu Ucar
The paper maps the human immune system across the lifespan using scRNA-seq and snATAC-seq, revealing unique infant immune signatures and age-related changes in immune cell populations.
Titas Grabauskas, Luke Trinity, Chris P. Verschoor…·Duygu Ucar
The paper uses single-cell profiling to show CMV drives clonal expansion of GZMK CD8 and Th1 cells in humans.