Structural and kinetic insights into a metagenomics-derived Cas12a with high specificity
Jacquelyn T. Wright, Satya Yendluri, Nicole C. Thomas, Cristina N. Butterfield, Tyler L. Dangerfield, David Ward Taylor
The paper characterizes Cas12a-MG29-1, a metagenomics-derived nuclease, revealing structural and kinetic features that enhance its specificity and activity.
bioRxiv · May 13, 2026 · PreprintBiochemistry