Aldosterone drives HSD2 neuron activity and molecular remodeling of synaptic function to promote sodium appetite
Miriam C. McDonough, Ahmet Kuralay, Trevor C. Butler, Berns Alysia, Schwager Madelin, Silvia Gasparini, Joel C. Geerling, Jon M. Resch
The paper shows aldosterone enhances synaptic transmission in HSD2 neurons through SV2C, driving sodium appetite.
bioRxiv · Oct 24, 2026 · PreprintNeuroscience