Gastrointestinal delivery of mRNA lipid nanoparticles selectively targets the pancreas
Abdulraouf M. Abbas, Ramy W. Ghanim, Sebastian Rudden, David P. Schultz, Avraham Shakked, Hyejin Kim, James E. Dahlman, Alex Abramson
This study shows that gastric delivery of cationic SM-102 LNPs significantly enhances pancreas targeting compared to intravenous delivery.
bioRxiv · Sep 15, 2025 · PreprintBioengineering