James E. Dahlman

This study develops a multi-point drug delivery system to improve myocardial drug distribution in swine, overcoming transport barriers caused by dense myocardial fibers.

PAVR enables high-resolution volumetric imaging of cells using a physics-aware framework trained on simulated data, demonstrating applications in tracking subcellular structures and analyzing cardiac cell dynamics.

This study uses CRISPR knockout and mechanical sorting to identify genes affecting cell stiffness in ovarian cancer, finding three genes linked to increased stiffness and patient survival.

This study develops a lymphatic endothelial cell-targeting lipid nanoparticle for mRNA delivery, improving lymphatic function after injury.

This study shows that gastric delivery of cationic SM-102 LNPs significantly enhances pancreas targeting compared to intravenous delivery.

This study demonstrates efficient in utero and neonatal lipid nanoparticle delivery for genome editing of hematopoietic stem cells, achieving robust editing and multilineage reconstitution.