p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition
Senthil K Radhakrishnan, Willem den Besten, Raymond J Deshaies
The paper shows that p97-dependent retrotranslocation and proteolytic processing of Nrf1 are essential for its activation upon proteasome inhibition.
bioRxiv · Jan 23, 2014Cell Biology