Author

Sergey Margasyuk

Skolkovo Institute of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2

Frequent Co-Authors

Dmitri Davidovich PervouchineiD· 3 shared Dmitry Aleksandrovich SkvortsoviD· 2 shared Maria VlasenokiD· 2 shared Marina V. PetrovaiD· 2 shared Alexei Mironov· 1 shared Andrey A. MironoviD· 1 shared Margarita A. Vorobeva· 1 shared О. А. ДонцоваiD· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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3 shared papersBioinformatics

Dmitri Davidovich PervouchineORCID

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Author profile →

3 papers

Recent·Most cited

BRD2 and BRD3 genes independently evolved RNA structures to control unproductive splicing

Marina V. Petrova, Sergey Margasyuk, Margarita A. Vorobeva, Dmitry Aleksandrovich Skvortsov, О. А. Донцова, Dmitri Davidovich Pervouchine

This study identifies conserved RNA structures in BRD2 and BRD3 genes that regulate unproductive splicing through poison exons, showing convergent evolution of splicing control mechanisms.

NAR Genomics and Bioinformatics · Dec 28, 2023Peer-reviewedBioinformatics

Tissue-specific regulation of gene expression via unproductive splicing

Alexei Mironov, Marina V. Petrova, Sergey Margasyuk, Maria Vlasenok, Andrey A. Mironov, Dmitry Aleksandrovich Skvortsov, Dmitri Davidovich Pervouchine

The paper identifies tissue-specific unproductive splicing events (USEs) regulated by RBPs using RNA-seq and RBP footprinting data from GTEx.

Nucleic Acids Research · Feb 24, 2023Peer-reviewedBioinformatics

Transcriptome sequencing suggests that pre-mRNAsplicing counteracts widespread intronic cleavage and polyadenylation

Maria Vlasenok, Sergey Margasyuk, Dmitri Davidovich Pervouchine

The paper identifies intronic polyadenylation sites and shows they are more common than exonic ones, suggesting splicing counteracts premature termination at these sites.

NAR Genomics and Bioinformatics · Jun 1, 2022Peer-reviewedBioinformatics