Long single-molecule reads can resolve the complexity of the Influenza virus composed of rare, closely related mutant variants
Alexander Artyomenko, Nicholas C Wu, Serghei Mangul, Eleazar Eskin, Ren Sun, Alex Zelikovsky
This paper introduces 2SNV, a method to accurately reconstruct rare viral mutant variants from single-molecule sequencing data with high sensitivity and accuracy.
Journal of Computational Biology · Jun 1, 2017Peer-reviewedBioinformatics