Harry Taegyun Yang

The paper identifies hnRNP H and F as regulators of Myc-dependent HRAS exon splicing in prostate cancer, showing their roles in splicing activation and correlation with Myc hallmarks.

IRIS identifies cancer immunotherapy targets from alternative splicing using transcriptomics data and validates them with patient T cells.

This study benchmarks error-correction methods for next-generation sequencing data, finding significant variation in performance across datasets with no single method being optimal overall.

The paper develops ImReP, a computational method to profile TCR and BCR repertoires from RNA-seq data, creating a large atlas of immunological sequences across 53 tissues.

This paper introduces ROP to identify the source of unmapped RNA-Seq reads across diverse tissues, showing it can account for 99.9% of 1 trillion reads and reveals immune and microbial correlations.

HapIso reconstructs haplotype-specific isoforms from long single-molecule reads by clustering reads into parental alleles despite high error rates.