Chemogenetic control of GABAergic activity within the interpeduncular nucleus reveals dissociable behavioral components of the nicotine withdrawal phenotype
Anabel M. M. Miguelez Fernández, Shana Netherton, Seshadri B. Niladhuri, Alexander C. Brown, Patricia Rivera, Kuei Yuan Tseng, Christian J. Peters
The paper uses chemogenetic approaches to show that Amigo1-expressing GABAergic neurons in the IPN are critical for anxiety-like behaviors during nicotine withdrawal, while Epyc-expressing neurons are not.
Neurobiology of Disease · Dec 22, 2025Peer-reviewedNeuroscience