Author

Seth Beadle

SUNY College of Environmental Science and Forestry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:Xenopus· 1 Organism:zebrafish· 1

Frequent Co-Authors

Andrew G. WagneriD· 1 shared Brian P. CallahaniD· 1 shared Dayton C. SeideliD· 1 shared John L. Pezzullo· 1 shared José‐Luis GineriD· 1 shared Katherine A. Thayer· 1 shared Margot L. Olejarczyk· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Andrew G. WagnerORCID

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1 paper

Recent·Most cited

In vitro reconstitution of vertebrate Sonic Hedgehog protein cholesterolysis

Dayton C. Seidel, Andrew G. Wagner, John L. Pezzullo, Katherine A. Thayer, Seth Beadle, Margot L. Olejarczyk, José‐Luis Giner, Brian P. Callahan

This study establishes an in vitro FRET-based assay to monitor cholesterolysis activity of vertebrate SHhC domains, revealing substrate specificity and identifying a conserved aspartate residue critical for activity.

bioRxiv · Mar 11, 2026 · PreprintBiochemistry