Author

Dayton C. Seidel

Binghamton UniversityORCID 0009-0005-4474-0769Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:Xenopus· 1 Organism:zebrafish· 1

Frequent Co-Authors

Andrew G. WagneriD· 1 shared Brian P. CallahaniD· 1 shared John L. Pezzullo· 1 shared José‐Luis GineriD· 1 shared Katherine A. Thayer· 1 shared Margot L. Olejarczyk· 1 shared Seth Beadle· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Andrew G. WagnerORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintMar 11, 2026

In vitro reconstitution of vertebrate Sonic Hedgehog protein cholesterolysis

Dayton C. Seidel, Andrew G. Wagner, John L. Pezzullo…·Brian P. Callahan

This study establishes an in vitro FRET-based assay to monitor cholesterolysis activity of vertebrate SHhC domains, revealing substrate specificity and identifying a conserved aspartate residue critical for activity.

DOI 10.64898/2026.03.09.710561

Xenopuszebrafish

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