The sequence of the extruded non-template strand determines the architecture of R-loops.
Yeraldinne Carrasco Salas, Amélie Malapert, Shaheen Sulthana, Bastien Molcrette, Léa Chazot-Franguiadakis, Pascal Bernard, Frederic L. Chedin, Cendrine Faivre-Moskalenko, Vincent Vanoosthuyse
This study shows that the sequence of the non-template strand determines the three-dimensional architecture of R-loops, which influences their impact on genome stability.
Nucleic Acids Research · Apr 26, 2019Peer-reviewedMolecular Biology