Shalini Saxena

C-Terminal Domain of Mycobacterium tuberculosis Glutamate Decarboxylase determines the bacterial stress-adaptive metabolic state that steers macrophage polarisation supporting intracellular persistence

This paper identifies the C-terminal domain of Mycobacterium tuberculosis GadB as critical for stress adaptation and macrophage polarisation, influencing infection outcomes through GABA production and ROS regulation.

The stage-specific regulation imposed by Importin beta-1 on HIV-1 propagation and infectivity dynamics

This study investigates how Importin beta-1 packaged in HIV-1 virions affects viral infectivity and transcription, revealing its dual role as both a facilitator and restriction factor.