MicrobiologybioRxivPreprint
C-Terminal Domain of Mycobacterium tuberculosis Glutamate Decarboxylase determines the bacterial stress-adaptive metabolic state that steers macrophage polarisation supporting intracellular persistence
Anushka Agarwal, Akash Misra, Shalini Saxena…·Sharmistha Banerjee
This paper identifies the C-terminal domain of Mycobacterium tuberculosis GadB as critical for stress adaptation and macrophage polarisation, influencing infection outcomes through GABA production and ROS regulation.
DOI 10.64898/2026.05.05.722917