Mitophagy upregulates WNT5A/Ca2+ signalling to accelerate fibroblast migration and wound healing
Matthew A. Hunt, Monica Torres, Nuoqi Wang, Shannon Hinch, Margarita Chatzopoulou, Gustavo Urbano-Quispe, Etty Bachar-Wikström, Jakob D. Wikström
This study shows that mitophagy enhances WNT5A/Ca2+ signaling to promote fibroblast migration and wound healing, with Urolithin A treatment improving healing outcomes.
bioRxiv · Dec 5, 2025 · PreprintDevelopmental Biology