Cannabidiol dose modulates behavioral response to acute and repeated administration of Δ9-Tetrahydrocannabinol by strain and sex
Sheena Saxena, Elizabeth A Duecker, Lukmon M. Raji, Christine E. Watkins, Sufiya Khanam, Byron C. Jones, Bob M. Moore II, Megan K. Mulligan
This study shows CBD modulates THC-induced behavioral changes in mice, varying by dose, sex, and genetic background, with no effect on antinociception.
bioRxiv · Mar 9, 2026 · PreprintAnimal Behavior & Cognition