Author

Shelley Lane

University of California, Irvine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Abigail Wiseman· 1 shared Derek S. Maranan· 1 shared Dylan D. Butler· 1 shared Frank M. LaFerlaiD· 1 shared Heather M. Terron· 1 shared Luke A. BurgardiD· 1 shared Malcolm A. LeissringiD· 1 shared Sagar J. Parikh· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

Abigail Wiseman

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Targeted control of gene expression using CRISPR-associated endoribonucleases

Sagar J. Parikh, Heather M. Terron, Luke A. Burgard, Derek S. Maranan, Dylan D. Butler, Abigail Wiseman, Frank M. LaFerla, Shelley Lane, Malcolm A. Leissring

This paper introduces DREDGE, a method using CRISPR-associated endoribonucleases to regulate gene expression by targeting direct repeats in the 3' untranslated region, achieving up to 90% downregulation in a reversible manner.

Cells · Apr 3, 2025Peer-reviewedMolecular Biology