Forward-reverse mutation cycles between stages of cancer development
Taobo Hu, Yogesh Kumar, Iram Shazia, Shen-Jia Duan, Yi Li, Lei Chen, Jin-Fei Chen, Rong Yin, Ava Kwong, Gilberto Ka-Kit Leung, Wai-Kin Mat, Zhenggang Wu, Xi Long, Cheuk-Hin Chan, Peggy Lee, , Hong Xue
The paper identifies forward-reverse mutation cycles in cancer development by analyzing LOHs and GOHs across non-tumor, paratumor, and tumor tissues in multiple cancer types.
bioRxiv · Oct 5, 2017 · PreprintCancer Biology