Hong Xue

Thermococci-to-Clostridia Pathway for the Evolution of the Bacteria Domain

The paper proposes a Thermococci-to-Clostridia evolutionary pathway as the origin of the Bacteria domain based on VARS-IARS similarity and phylogenetic analysis.

Copy number variation profile-based genomic subtyping of premenstrual dysphoric disorder in Chinese

The paper uses copy number variation (CNV) profiling to subtype premenstrual dysphoric disorder (PMDD) in Chinese patients, identifying CNV features that distinguish clinical subtypes with high accuracy.

Genetic-variant hotspots and hotspot clusters in the human genome facilitating adaptation while increasing instability

The paper identifies genetic-variant hotspots and clusters in the human genome, showing their dual role in promoting adaptation and genomic instability.

Forward-reverse mutation cycles between stages of cancer development

The paper identifies forward-reverse mutation cycles in cancer development by analyzing LOHs and GOHs across non-tumor, paratumor, and tumor tissues in multiple cancer types.