Transmission of Cervid Prions to Humanized Mice Demonstrates the Zoonotic Potential of CWD
Samia Hannaoui, Irina Zemlyankina, Sheng Chun Chang, Maria Immaculata Arifin, Vincent Béringue, Debbie I. McKenzie, Hermann M. Schätzl, Sabine Gilch
This study shows CWD prions can infect humanized mice, leading to atypical symptoms and transmissible infectivity, suggesting zoonotic potential and possible human transmission.
Acta Neuropathologica · Aug 22, 2022Peer-reviewedNeuroscience