Targeting the sinusoidal-to-capillarized transition to normalize vessels in breast cancer liver metastasis
Han-Ying Huang, Chuang Zhao, Xin-Nan Zheng, Shi Yan-xia, Lin Hai Tian
This study identifies Esm1 as a target for normalizing dysfunctional vessels in liver metastasis by showing its role in capillary tip cells and its correlation with poor prognosis.
bioRxiv · Oct 29, 2026 · PreprintCancer Biology