Shigeki Nakagome

PIGSTI detects species identity, pathogens, and microbes in ancient animal genomic data, identifying 15 zoonotic pathogens including Rickettsia felis and Leptospira borgpetersenii.

This study applies nanopore sequencing to ancient DNA from the Early Jomon period, demonstrating its ability to generate genome-wide data and enable rapid, on-site paleogenomic analysis.

The paper analyzes ancient genomes from Classic Copan, revealing a genetic continuum with dual ancestral structure between Mesoamerican and South American Farmer ancestry.

The paper uses statistical modeling on TCR sequence data to show that RAG scanning in the human TCR-α locus is bi-directional, with gene pairing preferences based on linear distance.

The paper analyzes the genome of a Jomon individual to infer migration patterns into East Asia, finding multiple waves and a coastal route from Southeast Asia.

The paper shows that CYP1B1 polymorphisms influence sexual dimorphism in medaka fish anal fin morphology.