Molecular BiologybioRxivPreprint
Parallel Arg/N-degron recognition systems regulate coenzyme A biosynthesis
Xiaolu Wang, Boju Wang, Liang Zhang…·Wenyi Mi
The paper identifies PANK1β and PANK3 as substrates of the Arg/N-degron pathway, revealing two distinct E3 ligase systems that regulate CoA biosynthesis through ubiquitin-dependent degradation.
DOI 10.64898/2026.09.15.751905