From pseudotime to true dynamics: reconstructing a real-time axis for T cells differentiation
Avishai Gavish, Benny Chain, Tomer‐Meir Salame, Yaron E. Antebi, Shir Katz, Shlomit Reich-Zeliger, Nir Friedman
The paper introduces a method to reconstruct real-time dynamics from single-cell trajectories by estimating cell density, flux, division, and apoptosis rates, validated on mouse thymus data.
bioRxiv · Jun 9, 2022 · PreprintSystems Biology