Author

Shireen Chikara

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Angelo Michael De MarzoiD· 1 shared Brian Wesley SimonsiD· 1 shared Bulouere Abel· 1 shared Fatima Rafiqi· 1 shared Jelani C. ZarifiD· 1 shared Kenji ZennamiiD· 1 shared Mindy Kim GrahamiD· 1 shared Polina Sysa‐ShahiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Angelo Michael De MarzoORCID

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1 paper

Recent·Most cited

Cell Type-Specific Effects of miR-21 Loss Attenuate Tumor Progression in MYC-Driven Prostate Cancer

Kenji Zennami, Mindy Kim Graham, Shireen Chikara, Polina Sysa‐Shah, Fatima Rafiqi, Rulin Wang, Bulouere Abel, Qizhi Zeng, Timothy E. G. Krueger, William Nathaniel Brennen, Sudipto Ganguly, Jelani C. Zarif, Brian Wesley Simons, Theodore L. DeWeese, Angelo Michael De Marzo, , Shawn E. Lupold

This study shows that loss of miR-21 in MYC-driven prostate cancer reduces tumor progression by affecting cell-type-specific gene regulation and immune infiltration.

bioRxiv · May 14, 2025 · PreprintCancer Biology