Author

William Nathaniel Brennen

Johns Hopkins UniversityORCID 0000-0001-9807-7433Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:dimensionality reduction· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Angelo Michael De MarzoiD· 1 shared Brian Wesley SimonsiD· 1 shared Bulouere Abel· 1 shared Daniel A.C. Fisher· 1 shared Daniel C. LinkiD· 1 shared Daniel L.J. ThorekiD· 1 shared Diane E. BenderiD· 1 shared Fatima Rafiqi· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Angelo Michael De MarzoORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 14, 2025

Cell Type-Specific Effects of miR-21 Loss Attenuate Tumor Progression in MYC-Driven Prostate Cancer

Kenji Zennami, Mindy Kim Graham, Shireen Chikara…·Shawn E. Lupold

This study shows that loss of miR-21 in MYC-driven prostate cancer reduces tumor progression by affecting cell-type-specific gene regulation and immune infiltration.

1 citation

mousescRNA-seq

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BioinformaticsNature CommunicationsPeer-reviewedMar 23, 2023

IMC-Denoise: a content aware denoising pipeline to enhance Imaging Mass Cytometry

Peng Lu, Karolyn A. Oetjen, Diane E. Bender…·Daniel L.J. Thorek

IMC-Denoise improves Imaging Mass Cytometry image quality by reducing noise and artifacts, enhancing downstream analysis.

68 citationstop 2%

humanimaging

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