Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction
James Boocock, Noah Alexander, Leslie Alamo Tapia, Laura Walter-McNeill, Shivani Prashant Patel, Chetan Munugala, Joshua S. Bloom, Leonid Kruglyak
The paper maps eQTLs in yeast using single-cell RNA sequencing, revealing tradeoffs between growth and reproduction through allele-specific effects on gene expression and cell-cycle progression.
eLife · Mar 12, 2025Peer-reviewedGenetics