Laura Walter-McNeill

The paper develops a pooled selection platform to map modifiers of RNAi gene knockdown effects in C. elegans, identifying two classes of QTL influencing RNAi responses.

The paper maps eQTLs in yeast using single-cell RNA sequencing, revealing tradeoffs between growth and reproduction through allele-specific effects on gene expression and cell-cycle progression.

The paper identifies a new TA system in C. elegans with divergent toxin alleles suppressed by distinct mechanisms, including piRNA-mediated silencing in the N2 haplotype.

This paper introduces a method to induce targeted recombination in C. elegans using Cas9, enabling high-resolution genetic mapping in species with low natural recombination rates.