Programmable Self-Assembly of RNA Nanostructures with >100 Unique Components
Liangxiao Chen, Zhishang Li, Jun Yan, Swarup Dey, Cong Li, Alexandra Petrova, Abhay Prasad, Deeksha Satyabola, Kira DeVore, Xinyi Tu, Yanzhe Qu, Shiyumou Wang, Gengshi Wu, Po‐Lin Chiu, Di Wen, , Di Liu
This paper introduces a method to create complex RNA nanostructures with over 100 unique components using dsRNA bricks, overcoming limitations of RNA scalability and stability.
bioRxiv · Sep 3, 2026 · PreprintSynthetic Biology