Author

Jun Yan

Gladstone InstitutesORCID 0000-0002-5641-5710Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jun Yan6 papers · China Agricultural University

Biology Disciplines

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Bioengineering· 1 Genetics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Abhay PrasadiD· 1 shared Alexander MarsoniD· 1 shared Alexandra Petrova· 1 shared Ansuman T. SatpathyiD· 1 shared Austin HartmaniD· 1 shared Britt AdamsoniD· 1 shared Cong Li· 1 shared Deeksha SatyabolaiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperSynthetic Biology

Abhay PrasadORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Prime editing enables high-throughput identification and characterization of selective MutSβ inhibitors

Yangwode Jing, Jun Yan, Denny Yang, Yanjin Chen, Issam Senoussi, James Woodward, Katya Williams, Hahn Kim, Kangning He, Herwin Daub, Vinay Dahiya, Maren Thomsen, Jia Ling, Purnima Ravisankar, Yuri Pritykin, , Britt Adamson

This study uses prime editing to identify and characterize MutSβ inhibitors that reduce (CAG)n repeat expansion.

bioRxiv · Oct 6, 2026 · PreprintBioengineering

Programmable Self-Assembly of RNA Nanostructures with >100 Unique Components

Liangxiao Chen, Zhishang Li, Jun Yan, Swarup Dey, Cong Li, Alexandra Petrova, Abhay Prasad, Deeksha Satyabola, Kira DeVore, Xinyi Tu, Yanzhe Qu, Shiyumou Wang, Gengshi Wu, Po‐Lin Chiu, Di Wen, , Di Liu

This paper introduces a method to create complex RNA nanostructures with over 100 unique components using dsRNA bricks, overcoming limitations of RNA scalability and stability.

bioRxiv · Sep 3, 2026 · PreprintSynthetic Biology

Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits

Ronghui Zhu, Emma Dann, Jun Yan, Justine Reyes Retana, Ryunosuke Goto, Reese C Guitche, Lillian Brixi, Mineto Ota, Austin Hartman, Theodore L. Roth, Ansuman T. Satpathy, Jonathan K. Pritchard, Alexander Marson

Genome-scale CRISPRi perturb-seq in 22 million primary human CD4+ T cells maps stimulation-specific regulators and links perturbation signatures to T cell states and autoimmune genetics.

Cell · Aug 28, 2026Peer-reviewedGenetics✦ In-depth digest