Author

Di Wen

Providence Portland Medical CenterORCID 0000-0003-4007-3856Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Abhay PrasadiD· 1 shared Alexandra Petrova· 1 shared Cong Li· 1 shared Deeksha SatyabolaiD· 1 shared Di LiuiD· 1 shared Dongxin ZhaoiD· 1 shared Gengshi Wu· 1 shared Guanglei ZhuangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

Abhay PrasadORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintSep 3, 2026

Programmable Self-Assembly of RNA Nanostructures with >100 Unique Components

Liangxiao Chen, Zhishang Li, Jun Yan…·Di Liu

This paper introduces a method to create complex RNA nanostructures with over 100 unique components using dsRNA bricks, overcoming limitations of RNA scalability and stability.

DOI 10.64898/2026.09.02.748990

experimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 31, 2025

Targeting CDK12 condensates at nuclear speckles with rationally designed cyclin K molecular glue degraders

Kaiyan Ye, Qinyang He, Yan Cheng…·Li Tan

This study identifies CDK12 condensates at nuclear speckles as a therapeutic target and demonstrates that cyclin K molecular glue degraders like HQY1428 disrupt these condensates, inhibiting oncogenic transcription and ovarian cancer growth.

1 citation

humanproteomics

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