EIF4A3 associated splicing and nonsense mediated decay defined by a systems analysis with novel small molecule inhibitors
Alborz Mazloomian, Shinsuke Araki, Momoko Ohori, Damian Yap, Shoichi Nakao, Atsushi Nakanishi, Sohrab P. Shah, Samuel A. J. R. Aparicio
The paper defines eIF4A3's role in splicing and NMD through a systems analysis using novel small molecule inhibitors and shows its link to cell cycle regulation.
bioRxiv · Sep 15, 2017 · PreprintGenomics