Leishmania donovani GP63 paralogues cooperatively orchestrate visceral infection and persistence
Debolina Manna, Sunandini Bhattacharya, Shounak Jana, Kristína Záhonová, Suvendu Nandi, Deneshraj Srinivasan, Nilanjan Pradhan, Nidhi Pandey, Debarati Biswas, Mahitosh Mandal, Gayatri Mukherjee, Vyacheslav Yurchenko, Budhaditya Mukherjee
This study identifies two essential GP63 paralogues in Leishmania donovani that cooperatively support visceral infection and persistence through distinct mechanisms.
bioRxiv · Nov 9, 2025 · PreprintMicrobiology