LARP1 senses free ribosomes to coordinate supply and demand of ribosomal proteins
James A. Saba, Zixuan Huang, Kate L. Schole, Xianwen Ye, Shrey D. Bhatt, Yi Li, Winston Timp, Jingdong Cheng, Rachel Green
This study shows LARP1 binds free ribosomal subunits to repress TOP mRNAs, coordinating ribosome protein synthesis with cellular demand.
bioRxiv · Nov 1, 2023 · PreprintMolecular Biology