Phosphatidylinositol 5 phosphate 4 kinase regulates phosphatidylinositol 3,4 bisphosphate levels in vivo.
Aishwarya Venugopal, Shreya Varma, Devaprabha Varsha, Padinjat Raghu
The paper shows that PIP4K regulates PI(3,4)P2 levels in Drosophila salivary gland cells through Class II PI3K activity, not directly via its catalytic function.
bioRxiv · Nov 24, 2025 · PreprintCell Biology