Emergence of carbapenem, beta-lactamase inhibitor and cefoxitin resistant lineages from a background of ESBL-producing Klebsiella pneumoniae and K. quasipneumoniae highlights different evolutionary mechanisms
Eva Heinz, Hasan Ejaz, Josefin Bartholdson Scott, Nancy Wang, Shruti Gujaran, Derek Pickard, Jonathan J. Wilksch, Hanwei Cao, Ikram ul Haq, Gordon Dougan, Richard A. Strugnell
The paper analyzes ESBL-producing Klebsiella strains to show dynamic resistance evolution and highlights that successful lineages are not necessarily the most resistant or virulent.
Scientific Reports · Feb 20, 2019Peer-reviewedGenomics