Author

Derek Pickard

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 3 Organism:E. coli· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Gordon DouganiD· 3 shared Abhilasha KarkeyiD· 1 shared Andrew J. PageiD· 1 shared Andrew John PollardiD· 1 shared Ann‐Mari Svennerholm· 1 shared Arun Gonzales DecanoiD· 1 shared Åsa SjölingiD· 1 shared Astrid von MentzeriD· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersGenomics

Gordon DouganORCID

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Author profile →

4 papers

Recent·Most cited

Long-read-sequenced reference genomes of the seven major lineages of enterotoxigenic Escherichia coli (ETEC) circulating in modern time

Astrid von Mentzer, Grace A. Blackwell, Derek Pickard, Christine J. Boinett, Enrique Joffré, Andrew J. Page, Ann‐Mari Svennerholm, Gordon Dougan, Åsa Sjöling

The paper generates high-quality reference genomes for seven major ETEC lineages using long-read sequencing, revealing conserved virulence plasmids crucial for pathogenesis.

Scientific Reports · Apr 29, 2021Peer-reviewedGenomics

Genomic surveillance of Escherichia coli ST131 identifies local expansion and serial replacement of subclones

Catherine Ludden, Arun Gonzales Decano, Dorota M. Jamrozy, Derek Pickard, Dearbháile Morris, Julian Parkhill, Sharon J. Peacock, Martin Cormican, Tim Downing

The paper analyzes global E. coli ST131 genomes to trace the evolution and spread of antibiotic-resistant subclones, identifying a C2 lineage that displaced a C1 strain in an Irish LTCF.

Microbial Genomics · Mar 26, 2020Peer-reviewedGenomics

Diagnostic host gene signature to accurately distinguish enteric fever from other febrile diseases

Christoph J. Blohmke, Julius Müller, Malick M. Gibani, Hazel Dobinson, Sonu Shrestha, Soumya Perinparajah, Celina Jin, Harri Hughes, Luke Blackwell, Sabina Dongol, Abhilasha Karkey, Fernanda Schreiber, Derek Pickard, Buddha Basnyat, Gordon Dougan, , Thomas C. Darton

The paper identifies a host gene signature using machine learning to distinguish enteric fever from other febrile diseases with high accuracy.

EMBO Molecular Medicine · Aug 30, 2019Peer-reviewedMolecular Biology

Emergence of carbapenem, beta-lactamase inhibitor and cefoxitin resistant lineages from a background of ESBL-producing Klebsiella pneumoniae and K. quasipneumoniae highlights different evolutionary mechanisms

Eva Heinz, Hasan Ejaz, Josefin Bartholdson Scott, Nancy Wang, Shruti Gujaran, Derek Pickard, Jonathan J. Wilksch, Hanwei Cao, Ikram ul Haq, Gordon Dougan, Richard A. Strugnell

The paper analyzes ESBL-producing Klebsiella strains to show dynamic resistance evolution and highlights that successful lineages are not necessarily the most resistant or virulent.

Scientific Reports · Feb 20, 2019Peer-reviewedGenomics