Harnessing Microbial Tools: Escherichia coli as a Vehicle for Neuropeptide Functional Analysis in Caenorhabditis elegans
Elizabeth M. DiLoreto, Shruti Shastry, Emily J Leptich, Douglas K. Reilly, Rachel N. Arey, Jagan Srinivasan
The paper develops a method to functionally analyze individual neuropeptides in C. elegans by expressing active peptides in E. coli and feeding them to loss-of-function mutants.
Genetics · Aug 6, 2025Peer-reviewedNeuroscience