Jagan Srinivasan

This study shows that S. aureus infection causes degeneration of nociceptive neurons in C. elegans, leading to impaired behavior and reduced neuronal function.

The paper develops a method to functionally analyze individual neuropeptides in C. elegans by expressing active peptides in E. coli and feeding them to loss-of-function mutants.

The paper identifies a serotonergic neural circuit in C. elegans that suppresses aversive responses to conflicting olfactory stimuli by inhibiting aversive signals.

This study shows DNA and RNA aptamers protect C. elegans and human cells from lead toxicity by mitigating reproductive, behavioral, and osteogenic effects.

The paper shows that the neurexin {gamma} isoform is required for glycerol avoidance in adult C. elegans, while other isoforms are needed in juveniles.

The paper shows that diverse states and stimuli modulate olfactory receptor expression in C. elegans to influence food-seeking behavior.

The paper identifies sex-specific receptor expression in C. elegans olfactory neurons and shows their non-redundant role in ascr#8 sensing.

The paper identifies a male-specific neuropeptide-receptor module that drives a sex-specific behavioral response to the pheromone ascr#8 in C. elegans.

The paper introduces a method to functionally rescue neuropeptide genes in C. elegans by feeding them bacteria expressing active peptides, revealing both redundant and unique functions of different neuropeptides.

The paper shows that a neurotransmitter receptor in C. elegans is co-opted for inter-organismal communication via pheromone sensing.

This study identifies sulfolipids secreted by predators that trigger fear-like responses in C. elegans through specific sensory neurons and signaling pathways.